Procymidone | 農藥合法資訊網

ProcymidoneisafungicidewhichiswidelyusedagainstBotrytiscinereaonwinegrapes.Ifimproperlyapplied,undesirableresiduesatconcentrationsranging ...

Animal experiments unequivocally show that some EDCs can induce cryptorchidism in rats and mice. Primarily, chemicals with antiandrogenic potential have been investigated. Classical antiandrogens (some of which are true AR antagonists) like the pesticides vinclozolin, procymidone, linuron, and prochloraz are indeed capable of inducing cryptorchidism but apparently do this primarily by interfering with the action of testosterone, whereas they appear to have no effect on Insl3 expression (Laier et al., 2006; Wilson, Blystone, Hotchkiss, Rider, & Gray, 2008; Wilson et al., 2004). Furthermore, the mild analgesic paracetamol appears to inhibit testosterone production specifically, leaving Insl3 levels unaffected (Kristensen et al., 2012). However, for one group of chemicals, namely, the phthalates, the mode of action seems to be somewhat different and to involve also INSL3. Even though pht...